This study aimed to investigate the value of DWI for monitoring soft tissue changes adjacent to bone during MR-guided HIFU. Using Sonalleve MR-guided HIFU system to perform ex-vivo experiments, the authors assessed the repeatability of the ADC measurement, the temporal evolution of ADC change after sonication, and its relationship with thermal parameters.

Article: Value of diffusion-weighted imaging for monitoring tissue change during magnetic resonance-guided high-intensity focused ultrasound therapy in bone applications: an ex-vivo study

Authors: Sharon L. Giles, Jessica M. Winfield, David J. Collins, Ian Rivens, John Civale, Gail R. ter Haar and Nandita M. deSouza